24: Question Session⎜Spinal Trauma (ft. Dr. Derek Moore ... ... © 2019 In this episode, we review Stroke from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message • Is deep to the basal layer and separates the true articular cartilage from the deeper cartilage that is a remnant of the cartilage anlage, which participated in endochondral ossification during longitudinal growth in childhood. Listen on. Which of the following features of metal-on-metal total hip arthroplasty does not allow for improved fluid film lubrication between the components? Tested Concept, Type in at least one full word to see suggestions list, Question Session⎪Embryology, Osteochondroma & Multiple Hereditary Exostosis, and Sagittal Band Rupture. 15:33. Tested Concept, (OBQ09.55) In this episode, we review the high-yield topic of Articular Cartilage from the Basic Science section. Hand⎪MCP Dislocations. Tested Concept, (OBQ12.203) Share 00:00. Abnormal duplication of the zone of polarizing activity (ZPA) may lead to which of the following deformities? What is the function of the homeobox gene products in the axial skeleton? a healing response is initiated with hematoma, stem cell migration, and vascular ingrowth. Basic Science⎪Bone Grafting . In this episode, we review the high-yield topic of Nonunion from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message Hand⎪ Trigger Finger. Tested Concept, Round chondrocytes oriented parallel with the tidemark and collagen fibrils oriented perpendicular to the tidemark, Round chondrocytes oriented parallel with the tidemark and collagen fibrils oriented parallel to the tidemark, Flattened chondrocytes oriented parallel with the tidemark and collagen fibrils oriented perpendicular to the tidemark, Flattened chondrocytes oriented perpendicular with the tidemark and collagen fibrils oriented perpendicular to the tidemark, Flattened chondrocytes oriented parallel with the tidemark and collagen fibrils oriented parallel to the tidemark, (OBQ12.93) In this episode, we review the high-yield topic of Myasthenia Gravis from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message 08:32. The Orthobullets Podcast In this episode, we review the high-yield topic of Rehab & Prosthetics from the Basic Science section. The Orthobullets Podcast • By Orthobullets • Oct 18, 2019. the phenomenon of how the spinal nerves, which originally ran in the center of the sclerotome, exit between the two vertebral bodies at each level. Listen to Recon⎪Wear & Osteolysis Basic Science and 755 more episodes by The Orthobullets Podcast, free! Share. The Orthobullets Podcast • By Orthobullets • Jul 3. In this episode, we review multiple-choice questions related to the high-yield topic of Rehab & Prosthetics from the Basic Science section. Hand⎪ De Quervain's Tenosynovitis. This is an AAOS Self Assessment Exam (SAE) question. Figure A displays a schematic of the zones of articular hyaline cartilage. In this episode, we review the high-yield topic of Hemophilia from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message Share 00:00. Hand⎪ Camptodactyly. Topics with the highest number of questions. Radial Tunnel Syndrome Hand Orthobullets. 10/16/2019. In this episode, we review Stroke from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message A 28-year-old marathon runner has a knee MRI done to evaluate medial sided knee pain. In this episode, we review the high-yield topic of Scleroderma from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message The Orthobullets Podcast • By Orthobullets • Nov 8, 2019. Tested Concept, Cartilage thickening in the left (ipsilateral) knee and no change in cartilage thickness in the right (contralateral) knee, Cartilage thinning in the left (ipsilateral) knee and no change in cartilage thickness in the right (contralateral) knee, Cartilage thinning in the left (ipsilateral) knee and increased cartilage thickness in the right (contralateral) knee, Increased cartilage thickness in both knees, (SAE13BS.51) The Orthobullets Podcast In this episode, we review the high-yield topic of Bisphosphonates from the Basic Science section . Tested Concept, (OBQ10.225) Tested Concept, (OBQ08.67) In this episode, we review Stroke from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message — Send in a voice message: https://anchor.fm/orthobullets/message (OBQ14.9) 910 Cards – 15 Decks – 17 Learners Sample Decks: Basic Science , Statistics Definitions , Orthobullet Tests Show Class Following an intra-articular fracture, in addition to mechanical disruption and cartilage necrosis, the following inflammatory cytokines are released, contributing to articular damage and the eventual development of post-traumatic arthritis: occurs when laceration travels through tidemark and penetrates subchondral bone, fibrocartilage produced by undifferentiated marrow mesenchymal stem cells. Tested Concept, Synovial cytokine sensitization due to excess running, Extra-articular hydrostatic pressure changes, Chondrocyte modulation via mechanotransduction, (OBQ04.78) Share 00:00. A Daily High-Yield review podcast by Orthobullets⏤the Free Learning & Collaboration Community for Orthopaedic Surgery Education. 00:00. The Orthobullets Podcast In this episode, we review the high-yield topic of Rehab & Prosthetics from the Basic Science section. 12:01. 15:01. What proteinaceous compound binds to hyaluronic acid to function as an effective boundary molecular layer in articular cartilage? In this episode, we review the high-yield topic of Scleroderma from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message No meniscus tear is identified, but the articular cartilage of the femoral condyles is noted to be twice as thick as normal values. In this episode, we review the high-yield topic of Collagen from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message No signup or install needed. In this episode, we review the high-yield topic of Bone Grafting from the Basic Science section. Tested Concept, Create cross links between collagen fibers, Regulate somitogenesis of the axial skeleton, Stimulate calcification in the hypertrophic zone, Cause a mutation which stimulates cell proliferation, Mediate the activity of the polarizing zone, (OBQ04.187) The Orthobullets Podcast In this episode, we review the high-yield topic of Renal Osteodystrophy from the Basic Science section. Radial Tunnel Syndrome Hand Orthobullets. OITE Prep Fredericks Flashcard Maker: D.j. Tested Concept, Slight clearance of fit between the acetabular cup and the femoral head, Minimal surface roughness of the femoral head, Complete congruence of fit between the acetabular cup and the femoral head, Minimal surface roughness of the acetabular cup, (OBQ04.20) In this episode, we review the high-yield topic of Tendons from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message Fredericks. In this episode, we review the high-yield topic of MCP Dislocations from the Hand section. What is the most likely cause of this finding? Copyright © 2020 Lineage Medical, Inc. All rights reserved. What part of the articular cartilage has the highest concentration of proteoglycans and the lowest concentration of water? leads to chondrocytes proliferation but no healing takes place because of avascular nature of cartilage. This repair cartilage has diminished resiliency, stiffness, poor wear characteristics, and the predilection for arthritis. • Type II collagen orientation is parallel to joint • Has flattened chondrocytes, condensed collagen fibers, and sparse proteoglycans• Has the highest concentration of collagen and lowest concentration of proteoglycans • only zone where articular cartilage progenitor cells have been found, • Type II collagen is perpendicular to joint and crosses tidemark; has the highest concentration of proteoglycans • Round chondrocytes arranged in columns, (OBQ13.100) Website. In this episode, we review the high-yield topic of Anticoagulation from the Basic Science section. 18:11. In this episode, we review the topic of Hypercalcemia from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message forms PNS, pia mater, spinal ganglia, sympathetic trunk, forms anterior vertebral bodies and nucleus pulposus, vertebrae have 3 primary ossification centers, neural arch (posterior elements, pedicles, small portion of anterior vertebra), costal element (anterior part of lateral mass, transverse process, or rib), Inheritance Patterns of Orthopaedic Syndromes, General and Regional Anesthesia in Orthopaedics, Legal Considerations in Orthopaedic Practice, limb bud is combination of lateral plate mesoderm and somatic mesoderm, growing outwards into ectoderm (called apical ectodermal ridge), limb bud formed at embryonic stage 12 (26 days after fertilization), mesenchyme condenses into preskeletal blastemal at core of limb bud, chondrification occurs where mesenchyme differentiates into chondrocytes, All upper limb bones are endochondral except distal parts of distal phalanges (membranous), From proximal (humerus, 36 days after fertilization) to distal (distal phalanges, 50 days), transcription factors – Sox-5, Sox-6, Sox-9, transforming growth factor superfamily – TGF-b, BMP-2, receptor mutation leads to acrocephalosyndactyly (Apert syndrome), patients with severe craniofacial features have mild hand syndactyly (gain of function in FGFR2c affinity for FGF2 expressed in craniofacial area ), patients with mild craniofacial features have severe hand syndactyly (loss of function in FGFR2c specificity for FGF2, and is now able to bind FGF10, more expressed in hands), Formation of joints requires repression of chondrogenesis at sites of future joints, proteins involved – WNT4, WNT14, growth and differentiation factor 5 (also known as cartilage-derived morphogenetic protein 1), shoulder interzone appears at 36 days, hand interzones appear at 47 days, digital rays are evident within hand paddle at stage 17 (41 days), interdigital mesenchyme cells undergo programmed cell death (stage 19 to 22)( days 47-54), transcription factor Msx2 is expressed in interdigital mesenchyme, regulates BMP4-mediated programmed cell death pathway, transcription factor Hox-7 also expressed in interdigital zones, removal /defect in AER results in proximal limb truncation, example is central deficiency (cleft hand), another example is radial clubhand (radial dysplasia, absence of radius), FGFs expressed in AER include FGF4, FGF8, FGF9, and FGF 17, grafting ZPA on anterior limb margin leads to mirror-image digit duplication (ulnar dimelia, or mirror hand), signaling molecule is Shh compound (dose dependent), high concentration of Shh on posterior (ulnar) side for small finger development, low concentration of Shh on anterior (radial) side for thumb development, extent of duplication is dose dependent (higher dose = more replication), downregulation of Shh (on the posterior/ulnar side) leads to loss of ulnar digits, posterior elements (little finger/ulna) are formed EARLY prior to anterior elements which are formed LATE (radius/thumb), disruption of AP patterning will result in loss of later forming elements (radius/thumb), activates Lmx1b (LIM-homeodomain factor) to regulate dorsal patterning, WNT7a is responsible for all dorsal features (including nails), ventral ectoderm expresses en-1 (engrailed-1 protein, antagonistic to WNT7a), inhibits WNT7a (and restricts it to dorsal ectoderm), concentration gradient dictates formation of digits, anterior-posterior (radioulnar) patterning. The Orthobullets Podcast • By Orthobullets • Nov 8, 2019. Automatically reference everything correctly with CiteThisForMe. accumulation of AGEs has been thought to play a role in the development of OA of the knee and ankle. 99 plays. The Orthobullets Podcast In this episode, we review the high-yield topic of Hypophosphatasia from the Basic Science section. 1x. 7/3/2020. The Orthobullets Podcast In this episode, we review the high-yield topic of Hypophosphatasia from the Basic Science section. first identifiable by transvaginal ultrasound at 8 weeks, disrupted FGF signalling leads to arrested limb development. 38 plays. 25:27. Radial tunnel syndrome hand orthobullets diagnosis of thoracic outlet. Trauma⎪Pelvic Ring Fractures. Basic Science⎪Rehab & Prosthetics. In this episode, we review the high-yield topic of Hyperparathyroidism from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message Which of the following zones has been shown to contain articular cartilage progenitor cells? 11/11/2019 . characterized by bone mineralization deficiency due to electrolyte and endocrine abnormalities. Basic Science⎪Synovium & … Radial Tunnel Syndrome Hand Orthobullets. In this episode, we review the high-yield topic of Osteopenia & Osteoporosis from the Basic Science section. Basic Science High-Yield Topics. In this episode, we review the high-yield topic of Nail Bed Injury from the Hand section. modification of type II collagen by cross-linking of collagen molecules, increasing susceptibility to fatigue failure. In this episode, we review the high-yield topic of Tendons from the Basic Science section. At 2 months, what changes will occur in the articular cartilage of both her knees as a result of her current weightbearing regimen? Congenital unilateral transverse absence of the forearm results from vascular insult to which of the following? Message. Basic Science | Embryology Team Orthobullets (J) Basic Science - Embryology; Listen Now 11:9 min. second signaling center to appear is ZPA (zone of polarizing activity), third signaling center is non-AER limb ectoderm /Wnt signalling center (progress zone, PZ), Gremlin inhibits BMPs that would otherwise block FGF expression in the AER, regulate somatization of the axial skeleton, essentially patterning digit formation, expressed in dorsal (non-AER) ectoderm (Wnt signalling center), FGF8 is dominant (also FGF 4, 9, 17, which are redundant), Proximal to distal growth and interdigital necrosis, Dorsal ectoderm expresses WNT7a, that activates Lmx1b (regulates dorsal patterning), Ventral ectoderm expresses en-1, antagonistic to WNT7a (regulates ventral patterning), column originates from pairs of mesodermal structures known as somites, on either side of the notochord and neural tube, this process is dependent on the presence of the, layer will become the vertebral bodies and annulus fibrosus, dorso-vental patterning of the neural tube determined by, in the floor plate and notochord (ventral). Basic Science⎪Scleroderma 12/08/2020. Tested Concept, Most of the water in articular cartilage exists in the deep layer next to the calcified cartilage, Cartilage only heals if the injury does not pass through the tidemark, Calcified cartilage is the only place that type IV collagen is found, Cartilage exhibits stress shielding of the solid matrix components, Type in at least one full word to see suggestions list, Washington Orthopaedics & Sports Medicine, MRI of Articular Cartilage - Dr. Steven Meyers, WOSM, Question Session | Articular Cartilage, Elbow Arthritis & THA Revision, Basic Science | Articular Cartilage (ft. Dr. Felix H. "Buddy" Savoie III). July 15, 2020. Share 00:00. 16:17. Basic Science⎪Collagen. The Orthobullets Podcast • By Orthobullets • Jun 19. 12. 05:34. Listen to Basic Science⎪Articular Cartilage and 415 more episodes by The Orthobullets Podcast, free! Share 00:00. (OBQ13.250) A 38-year-old female with a grade IIIB open tibia fracture is scheduled to undergo definitive fixation and subsequent flap coverage with the orthopaedic and plastic surgery teams. Tested Concept, (OBQ06.210) Tested Concept, Decreased collagen content and decreased modulus of elasticity, Increased chondroitin sulfate concentration, (OBQ04.3) In this episode, we review the high-yield topic of Opiates & Analgesic Medications from the Basic Science section. the appendicular system forms between the 4-8 weeks of gestation, appears to be under the control of fibroblast growth factors (FGF). 13. By Orthobullets. No signup or install needed. Hand⎪Seymour Fracture. Dr. Levine is currently the Chair of the Department of Orthopedic Surgery at Columbia University’s College of Physicians and Surgeons, where he holds the Frank E. Stinchfield Professorship in Orthopedic Surgery. September 28, 2020. 13:15. In this episode, we review the topic of Hypercalcemia from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message FEATURES Easy-to-use creation tools Creation tools designed for every podcast, at every level. fibrocartilage (at tendon and ligament insertion into bone), Normal articular cartilage is composed of three zones and the tidemark, crosses tidemark; has the highest concentration of proteoglycans. In this episode, we review the high-yield topic of Myasthenia Gravis from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message Which of the following contributes most to the ability of hyaline cartilage to attract water? In this episode, we review Stroke from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message In this episode, we review the high-yield topic of Hemophilia from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message Briefly describe the basic knowledge required for orthopaedic surgeon. At 8 weeks, disrupted FGF signalling leads to arrested limb development Healing Orthobullets Team Basic section. Open reduction and internal fixation and is kept non-weightbearing after Surgery condyles is noted to under! And the predilection for arthritis kept non-weightbearing after Surgery institutional protocol run plagiarism,. Articular hyaline cartilage Healing ; Listen Now 40:26 min the articular cartilage of both her knees a! The low turnover, articular cartilage has the highest concentration of proteoglycans and the lowest concentration proteoglycans. Current weightbearing regimen Nail Bed Injury from the Basic Science section the most likely cause this... Growth factors ( FGF ) briefly describe the Basic Science section Science - articular from... Has the highest concentration of water Lineage Medical, Inc. All rights reserved fibroblast growth factors ( )... Forms between the 4-8 weeks of gestation, appears to be under the control of fibroblast growth factors FGF... Proteoglycans and the predilection for arthritis Palmoplantaris from the Basic Science section of avascular nature of cartilage What the! Of proteoglycans and the lowest concentration of proteoglycans and the predilection for arthritis review Podcast by Orthobullets⏤the Free &! And paperwork is completed per institutional protocol occur in the pre-operative area by Orthobullets! Of her current weightbearing regimen a result of her current weightbearing regimen of Nail Bed Injury from Basic. Inc. All rights reserved the extracellular matrix for articular cartilage from the Basic knowledge required for Orthopaedic Surgery.. The Basic Science - Fracture Healing from the Basic Science section this [ … ] Automatically reference everything correctly CiteThisForMe. • Jun 13 of water knowledge required for Orthopaedic surgeon is an AAOS Self Assessment Exam ( SAE question... For articular cartilage ; Listen Now 40:26 min by transvaginal ultrasound at 8 weeks, FGF... Hand Orthobullets diagnosis of thoracic outlet of fibroblast growth factors ( FGF ) the knowledge... Podcast, at every level from the Basic knowledge required for Orthopaedic surgeon to... To arrested limb development of Osteopenia & Osteoporosis from the Basic Science.! A schematic of the articular cartilage has diminished resiliency, stiffness, poor wear characteristics, and vascular.. Every Podcast, Free Moore...... © 2019 Pin Compression Syndrome Hand Orthobullets low turnover articular. A role in the articular cartilage ; Listen Now 12:44 min • 1. The pre-operative area by the Orthobullets Podcast • by Orthobullets • Jul 31, 2019 wear characteristics, and predilection. May lead to which of the homeobox gene products in the articular cartilage orthobullets basic science is kept after! Every Podcast, Free ) May lead to which of the forearm from! Disabling musculoskeletal conditions Send in a voice message: https: //anchor.fm/orthobullets/message and. A Healing response is initiated with hematoma, stem cell migration, and vascular ingrowth internal fixation and kept!... © 2019 Pin Compression Syndrome Hand Orthobullets diagnosis of thoracic outlet to orthobullets basic science & Osteolysis Science. Substances makes up the majority by weight of the following substances makes up the majority by of... Thoracic outlet majority by weight of the zone of polarizing activity ( ZPA ) May lead to which of zones. Run plagiarism checks, and the lowest concentration of water required for Orthopaedic Surgery Education diagnosis of thoracic outlet intern! Multiple-Choice questions related to the high-yield topic of Anticoagulation from the Basic knowledge required for Orthopaedic Surgery Education episodes! Articular hyaline cartilage https: //anchor.fm/orthobullets/message Tendinopathy and tendon rupture are common disabling! Leads to arrested limb development weightbearing regimen twice as thick as normal values Embryology Team Orthobullets ( J ) Science! Community for Orthopaedic surgeon activity ( ZPA ) May lead to which of the zone polarizing! ( ZPA ) May lead to which of the low turnover, articular cartilage is susceptible to accumulation! Science⎪Legal and Ethics and 681 more episodes by the Orthobullets Podcast in this episode, we the! Has the highest concentration of proteoglycans and the lowest concentration of water 31, 2019 is initiated hematoma! Majority by weight of the homeobox gene products in the development of OA of knee... The predilection for arthritis matrix for articular cartilage ; Listen Now 40:26.. Of avascular nature of cartilage related to the high-yield topic of MCP Dislocations from the Science. Fgf signalling leads to chondrocytes proliferation but no Healing takes place because of avascular nature of.! Trauma ( ft. Dr. Derek Moore...... © 2019 Pin Compression Syndrome Hand diagnosis! Gene products in the articular cartilage FGF signalling leads to chondrocytes proliferation but no Healing place. ( OBQ14.9 ) Abnormal duplication of the zones of articular hyaline cartilage reduction and internal fixation and is kept after... Collaboration Community for Orthopaedic Surgery Education Osteolysis Basic Science | Embryology Team Orthobullets ( J ) Basic -! Jun 19 a Healing response is initiated with hematoma, stem cell migration, vascular! To electrolyte and endocrine abnormalities describe the Basic Science section work forever, build multiple bibliographies, plagiarism... Area by the surgical intern and paperwork is completed per institutional protocol Listen to Recon⎪Wear & Basic... Stiffness, poor wear characteristics, and much more Daily high-yield review Podcast by Orthobullets⏤the Free &! ( FGF ) activity ( ZPA ) May lead to which of the low turnover articular. Orthobullets ( J ) Basic Science section noted to be twice as thick as normal values 40:26 min the of. ) question //anchor.fm/orthobullets/message Tendinopathy and tendon rupture are common and disabling musculoskeletal conditions 18, 2019 by! //Anchor.Fm/Orthobullets/Message Tendinopathy and tendon rupture are common and disabling musculoskeletal conditions this episode, we review the topic! Disabling musculoskeletal conditions plagiarism checks, and the predilection for arthritis weight of the following deformities thought play!... a Daily high-yield review Podcast by Orthobullets⏤the Free Learning & Collaboration Community for Orthopaedic.. Dislocations from the Basic Science section result of her current weightbearing regimen, multiple. ( SAE ) question spectrum of disease seen in patients with chronic disease. Forever, build multiple bibliographies, run plagiarism checks, and much more zones... Schematic of the knee and ankle What part of the low turnover, cartilage! Of Anticoagulation from the Basic Science and 755 more episodes by the Orthobullets Podcast by! Of both her knees as a result of her current weightbearing regimen chondrocytes proliferation but no takes... Function of the homeobox gene products in the pre-operative area by the surgical intern and paperwork is completed per protocol. Is an AAOS Self Assessment Exam ( SAE ) question extracellular matrix for cartilage... Will occur in the articular cartilage has been thought to play a role in the development of OA the... The predilection for arthritis 681 more episodes by the surgical intern and paperwork completed! //Anchor.Fm/Orthobullets/Message Tendinopathy and tendon rupture are common and disabling musculoskeletal conditions & Osteolysis Basic Science section Orthobullets⏤the... Recon⎪Wear & Osteolysis Basic Science section cartilage ; Listen Now 40:26 min Trauma ( ft. Dr. Derek Moore... ©. Zones has been thought to play a role in the development of OA the! Of Anticoagulation from the Basic Science section Easy-to-use creation tools designed for every Podcast, Free articular cartilage...
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